Monday, February 7, 2011

Cannabinoids Kill Cancer and Our Government Has Known for 36 Years

http://www.gsalternative.com/2010/05/cannabinoids-kill-cancer/

Cannabinoids Kill Cancer and Our Government Has Known for 36 Years

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Below is a repost of an article published on Americans for Safe Access website: www.safeaccessnow.org in November of 2003. The article describes how cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals and also kill cancer cells. Then it finishes off by saying that the US government has known for more than 35 years and that the media which would normally go crazy about a cancer cure story like this, doesn’t at all and in fact seem to be burying the story rather than promote it in any way. I for one am amazed at the government’s stance on marijuana and their failed war on drugs, which is more like a war on it’s own country. I guess too many people get rich off of the war on drugs. Read the full story after the break.

by Steve Kubby, Sierra Times
November 10th, 2003

A new study published in Nature Reviews-Cancer provides an historic and detailed explanation about how THC and natural cannabinoids counteract cancer, but preserve normal cells.

The study by Manuel Guzmán of Madrid Spain found that cannabinoids, the active components of marijuana, inhibit tumor growth in laboratory animals. They do so by modulating key cell-signalling pathways, thereby inducing direct growth arrest and death of tumor cells, as well as by inhibiting the growth of blood vessels that supply the tumor.

The Guzman study is very important according to Dr. Ethan Russo , a neurologist and world authority on medical cannabis: “Cancer occurs because cells become immortalized; they fail to heed normal signals to turn off growth. A normal function of remodelling in the body requires that cells die on cue. This is called apoptosis, or programmed cell death. That process fails to work in tumors. THC promotes its reappearance so that gliomas, leukemias, melanomas and other cell types will in fact heed the signals, stop dividing, and die.”

“But, that is not all,” explains Dr. Russo: “The other way that tumors grow is by ensuring that they are nourished: they send out signals to promote angiogenesis, the growth of new blood vessels. Cannabinoids turn off these signals as well. It is truly incredible, and elegant.”

In other words, this article explains several ways in which cannabinoids might be used to fight cancer, and, as the article says, “Cannabinoids are usually well tolerated, and do not produce the generalized toxic effects of conventional chemotherapies.

Usually, any story that even suggests the possibility of a new treatment for cancer is greeted with headlines about a “cancer cure” – however remote in the future and improbable in fact it might be. But if marijuana is involved, don’t expect any coverage from mainstream media, especially since mainstream editors have been quietly killing this story for the past thirty years…

That’s right, news about the abilility of pot to shrink tumors first surfaced, way back in 1974. Researchers at the Medical College of Virginia, who had been funded by the National Institutes of Health to find evidence that marijuana damages the immune system, found instead that THC slowed the growth of three kinds of cancer in mice — lung and breast cancer, and a virus-induced leukemia.

The Washington Post reported on the 1974 study — in the “Local” section — on Aug. 18, 1974. Under the headline, “Cancer Curb Is Studied,” it read in part: “The active chemical agent in marijuana curbs the growth of three kinds of cancer in mice and may also suppress the immunity reaction that causes rejection of organ transplants, a Medical College of Virginia team has discovered.” The researchers “found that THC slowed the growth of lung cancers, breast cancers, and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent.”

“News coverage of the Madrid discovery has been virtually nonexistent in this country. The news broke quietly on Feb. 29, 2000 with a story that ran once on the UPI wire about the Nature Medicine article,” complained MarijuanaNews.com editor Richard Cowan , who said he was only able to find the article through a link that appeared briefly on the Drudge Report Web page. “The New York Times, The Washington Post, and Los Angeles Times all ignored the story, even though its newsworthiness is indisputable: a benign substance occurring in nature destroys deadly brain tumors,” added Cowan.

On March 29, 2001, the San Antonio Current printed a carefully researched, bombshell of a story by Raymond Cushing titled, “POT SHRINKS TUMORS; GOVERNMENT KNEW IN ‘74.” Media coverage since then has been nonexistant, except for a copy of the story on Alternet.

It is hard to believe that the knowledge that cannabis can be used to fight cancer has been suppressed for almost thirty years , yet it seems likely that it will continue to be suppressed. Why?

According to Cowan, the answer is because it is a threat to cannabis prohibition . “If this article and its predecessors from 2000 and 1974 were the only evidence of the suppression of medical cannabis, then one might perhaps be able to rationalize it in some herniated way. However, there really is massive proof that the suppression of medical cannabis represents the greatest failure of the institutions of a free society, medicine, journalism, science, and our fundamental values,” Cowan notes.

Millions of people have died horrible deaths and in many cases, familes exhausted their savings on dangerous, toxic and expensive drugs. Now we are just beginning to realize that while marijuana has never killed anyone, marijuana prohibition has killed millions.

Friday, January 28, 2011

Lab tests are in ...

A recent hemp oil submission to CW Analytical for testing, and here were the results...

Thursday, January 6, 2011

Breaking News: Popular Cancer Drug Declared More Harmful Than Helpful

Breaking News: Popular Cancer Drug Declared More Harmful Than Helpful

Posted By Dr. Mercola | January 07 2011 | 8,258 views


The FDA has said that the controversial drug Avastin should be phased out as a treatment for metastatic breast cancer. Recent studies show that its benefits are outweighed by dangerous side effects.


The announcement does not affect Avastin's status as a drug that can be prescribed for lung cancer, kidney cancer, colorectal cancer and brain cancer.

In 2008, the FDA granted Avastin accelerated approval for use to treat metastatic breast cancer. But studies have failed to show that patients getting Avastin lived longer than patients on standard chemotherapies.

According to CNN:

"Along with those disappointing findings, serious side effects became apparent in patients taking Avastin, including high blood pressure, internal bleeding, perforated internal organs, heart failure and heart attacks, and in some cases, even swelling of the brain."


Genentech, which makes Avastin, has a right to appeal the decision.

Folks, the best way of preventing breast cancer isn't a drug at all, and it's free!

Sun exposure may be the single most effective means of reducing breast cancer, thanks to vitamin D, which forms in your body in reaction to sunlight. In a recent study, data collected over a decade from more than 67,000 women showed that women in sunny climes with high vitamin D levels were at a significantly reduced risk of breast cancer!
Sources:
CNN December 16, 2010
Cancer Epidemiology, Biomarkers and Prevention December 2, 2010


Dr. Mercola's Comments:

Surgery, drugs and radiation are typically the only solutions offered by conventional physicians to treat cancer, and upon receiving a cancer diagnosis most people are willing to do just about anything to get better. This includes taking dangerous and outrageously expensive medications that offer little, if any, benefit.

Case in point: Avastin.

Popular Breast Cancer Drug Proven More Harmful than Helpful

Avastin, which costs about $8,000 a month and is one of the best-selling cancer drugs in the world, is now being phased out in the US due to lack of effectiveness and dangerous side effects.

As reported by CNN, the FDA has deemed the drug to be more harmful than beneficial based on recent studies, and recommends phasing it out as a treatment for metastatic breast cancer.

The drug will still maintain its status as an approved therapy for lung-, kidney-, colorectal- and brain cancer, however.

The European Medicines Agency is also altering its recommendation, but rather than withdrawing approval entirely, Avastin will now only be prescribed in combination with the drug Paclitaxel for the treatment of breast cancer in the EU.

CNN reports:

"Along with the initial approval, the FDA required Genentech, Avastin's maker, to complete larger studies. The results of those studies were a bitter pill for patients thriving on Avastin and researchers excited by the promise of the early data.

The E2100 study found that for women taking Avastin plus Paclitaxel, the cancer stopped spreading for an average of five-and-a-half months more, compared to those just taking standard chemotherapy.

In the subsequent three larger studies, the benefit was much smaller, ranging from just 24 days to about two months.

None of the studies, including the E2100 study, showed that patients getting Avastin lived longer than patients on standard chemotherapies. "We now have four studies that show no survival benefit," Woodcock said."

Serious side effects from the drug have also become apparent, including:

* High blood pressure
* Internal bleeding
* Perforated internal organs
* Heart failure
* Heart attacks
* Swelling of the brain


Avastin isn't the only popular cancer drug that's come on the chopping block in recent years.

For example, in 2009 it was determined that long-term use of the common breast cancer drug Tamoxifen could increase your risk of developing a deadly second tumor.

Chemotherapy—Cancer Patients' Friend or Foe?

Chemo is another cancer treatment that frequently does more harm than good, although I doubt we'll see recommendations changing on its use anytime soon.
As poor a choice as it is, it's one of the most popular treatment strategies conventional medicine has been able to conjure.

But despite its reputation as the gold-standard in cancer treatment, chemotherapy has an average 5-year survival success rate of just over 2 percent for all cancers, according to a study published in the journal Clinical Oncology in December 2004.

Another study, The National Confidential Enquiry into Patient Outcome and Death (NCEPOD), found that more than four in 10 patients who received chemotherapy toward the end of life experienced potentially fatal effects. And after reviewing data from over 600 cancer patients who died within 30 days of receiving treatment, it was found that chemotherapy hastened or caused death in 27 percent of those cases.

It's important to realize that chemotherapy drugs are, by their very nature, extremely toxic and typically do not work with your body to modulate and normalize its response to allow the cancer to resolve normally and they do absolutely nothing to address the cause of the cancer.

Natural approaches, on the other hand, do not have the types of fatal side effects common with cancer drugs because they work by optimizing your body's own natural healing capacities. And, fortunately, there are natural approaches that rival and/or exceed the limited effectiveness of conventional therapies, without the risks.

The caveat, however, is that you must typically use them preventively.

Two of the most important preventive strategies are vitamin D and diet.

Sunday, September 19, 2010

Understanding How THC Kills Cancer in Humans by Dennis Hill

Understanding How THC Kills Cancer in Humans

First let’s look at what keeps cancer cells alive, then we will come back and examine
how THC unravels cancer’s aliveness.
In every cell there is a family of interconvertible sphingolipids that specically manage the life and death of that cell. is pro le of factors is called the “Sphingolipid Rheostat.” If ceramide (a signaling metabolite of sphingosine-1-phosphate) is high, then cell death (apoptosis) is imminent. If ceramide is low, the cell is strong in its aliveness.
Very simply, when THC connects to the CB1 or CB2 cannabinoid receptor site on the
cancer cell, it causes an increase in ceramide synthesis which drives cell death. A normal healthy cell does not produce ceramide in the presence of THC, thus is not affected by the cannabinoid.
The cancer cell dies, not because of cytotoxic chemicals, but because of a tiny little shift in the mitochondria. Within most cells there is a cell nucleus, numerous
mitochondria (hundreds to thousands), and various other organelles in the cytoplasm. The purpose of the mitochondria is to produce energy (ATP) for cell use. As ceramide starts to accumulate, turning up the Sphingolipid Rheostat, it increases the mitochondrial membrane pore permeability to cytochrome c, a critical protein in energy synthesis. Cytochrome c is pushed out of the mitochondria, killing the source of energy for the cell.
Ceramide also causes genotoxic stress in the cancer cell nucleus generating a protein
called p53, whose job it is to disrupt calcium metabolism in the mitochondria. If this weren’t enough, ceramide disrupts the cellular lysosome, the cell’s digestive system that provides nutrients for all cell functions. Ceramide, and other sphingolipids, actively inhibit pro-survival pathways in the cell leaving no possibility at all of cancer cell survival.
The key to this process is the accumulation of ceramide in the system. is means
taking therapeutic amounts of THC, steadily, over a period of time, keeping metabolic
pressure on this cancer cell death pathway.
How did this pathway come to be? Why is it that the body can take a simple plant
enzyme and use it for profound healing in many di erent physiological systems? is
endocannabinoid system exists in all animals of creation, just waiting for it’s matched exocannabinoid activator.
This is amazing. Our own endocannabinoid system covers all cells and nerves; it is the messenger of information owing between our immune system and the central nervous
system (CNS). It is responsible for neuroprotection, and micro-manages the immune
system. is is the primary control system that maintains homeostasis; our well being.
Just out of curiosity, how does the work get done at the cellular level, and where does the body make the endocannabinoids? Here we see that endocannabinoids have their origin in nerve cells right at the synapse. When the body is compromised through illness or injury it calls desperately to the endocannabinoid system and directs the immune system to bring healing. If these homeostatic systems are weakened, it should be no surprise that exocannabinoids are therapeutic. It helps the body in the most natural way possible.
To see how this works we visualize the cannabinoid as a three dimensional molecule,
where one part of the molecule is configured to fit the nerve or immune cell receptor site just like a key in a lock. There are at least two types of cannabinoid receptor sites, CB1 (CNS) and CB2 (immune). In general CB1 gives us the buzz, and CB2 activates the immune system, but it’s much more complex than this. Both THC and anandamide activate both receptor sites. Other cannabinoids activate one or the other receptor sites. Among the strains of Cannabis, C. sativa tends toward the CB1 receptor, and C. indica tends toward CB2. So sativa is better for buzz, and indica is better for healing. Another factor here is that sativa is dominated by THC cannabinoids, and indica is predominately CBD (cannabidiol).
It is said that THC and CBD are biomimetic to anandamide, that is, the body can use
both interchangeably. Thus, when stress, injury, or illness demand more from endogenous anandamide than can be produced by the body, its mimetic exocannabinoids can rush to the rescue. If the stress is transitory, then the treatment can be transitory. If the demand is sustained, such as in cancer, then treatment needs to provide sustained pressure of the modulating agent on the homeostatic systems.
Typically CBD gravitates to the densely packed CB2 receptors in the spleen, home to
the body’s immune system. From there, immune cells seek out and destroy cancer cells.
Interestingly, it has been shown that THC and CBD cannabinoids have the ability to kill cancer cells directly without going through immune intermediaries. THC and CBD hijack the lipoxygenase pathway to directly inhibit tumor growth. As a side note, it has been discovered that CBD inhibits anandamide reuptake. is means that cannabidiol helps the body preserve its own natural endocannabinoid by inhibiting the enzyme that breaks down anandamide.
This brief survey touches lightly on a few essential concepts. Mostly I would like to
leave you in complete amazement that nature has designed the perfect medicine that ts
exactly with our own immune system of receptors and signaling metabolites to provide
perfect health all the time. It is my hope that my own prostate cancer dies out quickly in the face of intensive cannabis extract treatment currently in progress. The C-T Scan will tell the story next month.

~Dennis Hill
Legal in California


Bibliography

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Scientists test medicinal marijuana against MS, inflammation and cancer
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29425